BDBM328525 (S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(acetamidomethyl)-4-((1- (difluoromethyl)-3-ethoxy-1H- pyrazol-4-yl)sulfonyl)-3,4-dihydro- 2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 10AZ

SMILES CCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(C)=O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12)C(F)F

InChI Key InChIKey=DUROAWXXRSSWQT-AWEZNQCLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328525   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328525((S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(aceta...)
Affinity DataIC50:  4.38nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent