BDBM328740 (S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((3- chloro-4- fluorophenyl)sulfonyl)-2-((2- hydroxy-2- methylpropanamido)methyl)- 3,4-dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34AS
SMILES CC(C)(O)C(=O)NC[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(Cl)c1
InChI Key InChIKey=ZRCNITMAEGTHQX-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328740
Affinity DataIC50: 3.49nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair