BDBM328771 1,1,1-trifluoro-2-methylpropan- 2-yl ((2S)-4-((3-chloro-4- fluorophenyl)sulfonyl)-2- ((tetrahydrofuran-2- carboxamido)methyl)-3,4- dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34BX
SMILES CC(C)(OC(=O)Nc1ccc2O[C@@H](CNC(=O)C3CCCO3)CN(c2c1)S(=O)(=O)c1ccc(F)c(Cl)c1)C(F)(F)F
InChI Key InChIKey=TYPWFZPKCBITLP-ZDGMYTEDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328771
Affinity DataIC50: 4.47nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair