BDBM328797 1,1,1-trifluoro-2-methylpropan- 2-yl ((S)-4-((1- (difluoromethyl)-3-ethoxy-1H- pyrazol-4-yl)sulfonyl)-2- (((1S,2S)-2- fluorocyclopropane- carboxamido)methyl)-3,4- dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34CY
SMILES CCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)[C@@H]2C[C@@H]2F)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12)C(F)F
InChI Key InChIKey=QQUKTKJIVGHERC-ZNMIVQPWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328797
Affinity DataIC50: 3.07nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair