BDBM328798 (S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((1- (difluoromethyl)-3-ethoxy-1H- pyrazol-4-yl)sulfonyl)-2-((2- hydroxy-2- methylpropanamido)methyl)- 3,4-dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34CZ
SMILES CCOc1nn(cc1S(=O)(=O)N1C[C@H](CNC(=O)C(C)(C)O)Oc2ccc(NC(=O)OC(C)(C)C(F)(F)F)cc12)C(F)F
InChI Key InChIKey=FIHNTPGNCXQBOW-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328798
Affinity DataIC50: 3.86nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair