BDBM328814 (S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((3-cyanophenyl)sulfonyl)-2- (cyclopropanesulfonamidomethyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 36J

SMILES CC(C)(OC(=O)Nc1ccc2O[C@@H](CNS(=O)(=O)C3CC3)CN(c2c1)S(=O)(=O)c1cccc(c1)C#N)C(F)(F)F

InChI Key InChIKey=QTQJHZNDQSDZMW-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328814   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328814((S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((3-cya...)
Affinity DataIC50:  4.27nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent