BDBM328818 (S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((3-chloro-4-fluorophenyl)sulfonyl)- 2-(cyclopropanesulfonamidomethyl)- 3,4-dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 36N
SMILES CC(C)(OC(=O)Nc1ccc2O[C@@H](CNS(=O)(=O)C3CC3)CN(c2c1)S(=O)(=O)c1ccc(F)c(Cl)c1)C(F)(F)F
InChI Key InChIKey=MOXWJTAFKMNHRS-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328818
Affinity DataIC50: 4.35nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair