BDBM328821 (S)-4-((6-((tert- butoxycarbonyl)amino)-2- (cyclopropanesulfonamidomethyl)-2H- benzo[b][1,4]oxazin-4(3H)- yl)sulfonyl)-1-(difluoromethyl)-3- methyl-1H-pyrazole::US9663502, 36Q

SMILES Cc1nn(cc1S(=O)(=O)N1C[C@H](CNS(=O)(=O)C2CC2)Oc2ccc(NC(=O)OC(C)(C)C)cc12)C(F)F

InChI Key InChIKey=OTBYDNJKLIKXEM-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328821   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328821((S)-4-((6-((tert- butoxycarbonyl)amino)-2- (cyclop...)
Affinity DataIC50:  3.96nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent