BDBM328840 (S)-1,1,1-trifluoro-2-methylpropan-2-yl (4-((3-chloro-4-fluorophenyl)sulfonyl)- 2-(methylsulfonamidomethyl)-3,4- dihydro-2H-benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 37J
SMILES CC(C)(OC(=O)Nc1ccc2O[C@@H](CNS(C)(=O)=O)CN(c2c1)S(=O)(=O)c1ccc(F)c(Cl)c1)C(F)(F)F
InChI Key InChIKey=BKKMTNVBSSCHAJ-ZDUSSCGKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328840
Affinity DataIC50: 3.05nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair