BDBM328935 2,2,2-trifluoro-1,1-dimethylethyl [(2S)-4- {[2-(2-hydroxyethoxy)pyrazolo[1,5- a]pyridin-3-yl]sulfonyl}-2-{[(2-hydroxy- 2-methylpropanoyl)amino]methyl}-3,4- dihydro-2H-1,4-benzoxazin-6- yl]carbamate::US9663502, 12P

SMILES CC(C)(O)C(=O)NC[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1c(OCCO)nn2ccccc12

InChI Key InChIKey=YGFZOOGDBVHTQP-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328935   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328935(2,2,2-trifluoro-1,1-dimethylethyl [(2S)-4- {[2-(2-...)
Affinity DataIC50:  3.80nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent