BDBM328940 2,2,2-trifluoro-1,1-dimethylethyl [(2S)-2- [(acetylamino)methyl]-4-{2-(2- hydroxyethoxy)pyrazolo[1,5-a]pyridin-3- yl]sulfonyl}-3,4-dihydro-2H-1,4- benzoxazin-6-yl]carbamte::US9663502, 12U

SMILES CC(=O)NC[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1c(OCCO)nn2ccccc12

InChI Key InChIKey=FAGBZRJCQKDJKR-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328940   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328940(2,2,2-trifluoro-1,1-dimethylethyl [(2S)-2- [(acety...)
Affinity DataIC50:  4.01nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent