BDBM329518 2-((1S,2S)-2-((5-(5- methoxyimidazo[1,2- a]pyridin-7-yl)-2- methylpyrimidin-4- yloxy)methyl)cyclopropyl) quinoline::US9663513, 131

SMILES COc1cc(cc2nccn12)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc2ccccc2n1

InChI Key InChIKey=PRSJUOFYPWSJMS-UXHICEINSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329518   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329518(2-((1S,2S)-2-((5-(5- methoxyimidazo[1,2- a]pyridin...)
Affinity DataKi:  0.0400nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent