BDBM329540 2-((1S,2S)-2-((2-methyl- 5-(2-methylpyridin-4- yl)pyrimidin-4- yloxy)methyl)cyclopropyl) quinoline::US9663513, 153

SMILES Cc1cc(ccn1)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc2ccccc2n1

InChI Key InChIKey=OKHAUSZHQHCLEU-UXHICEINSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329540   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329540(2-((1S,2S)-2-((2-methyl- 5-(2-methylpyridin-4- yl)...)
Affinity DataKi:  0.0100nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent