BDBM329658 US11001583, Compound 14::US9663515, Compound 14

SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](COCC(O)=O)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1

InChI Key InChIKey=GBIVZPGJEONENR-BADNYSQJSA-N

Data  2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329658   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals, LLC

US Patent
LigandPNGBDBM329658(US11001583, Compound 14 | US9663515, Compound 14)
Show SMILES CCS(=O)(=O)c1ccc(cc1)[C@H](COCC(O)=O)NC(=O)c1cnc2[C@H](C(C)C)N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)Cc2c1
Show InChI InChI=1S/C31H40F3N3O6S/c1-4-44(41,42)25-11-7-21(8-12-25)26(17-43-18-27(38)39)36-30(40)22-13-23-16-37(29(19(2)3)28(23)35-14-22)15-20-5-9-24(10-6-20)31(32,33)34/h7-8,11-14,19-20,24,26,29H,4-6,9-10,15-18H2,1-3H3,(H,36,40)(H,38,39)/t20-,24-,26-,29-/m0/s1
Affinity DataKi: <100nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid