BDBM330044 (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-trifluoroethyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2, 1-b][1,3]oxazepine-10-carboxamide::US10689399, Compound 36::US11548901, Compound 36::US9663528, 36::US9732092, Compound 36

SMILES Oc1c2C(=O)N3[C@@H]4CC[C@@H](C4)OC3Cn2cc(C(=O)N[C@@H](c2ccc(F)cc2F)C(F)(F)F)c1=O

InChI Key InChIKey=UXQSJQPEHLONRU-ATIULZLMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 330044   

TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330044( (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-...)
Affinity DataIC50:  1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330044( (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-...)
Affinity DataIC50:  1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPOU domain, class 2, transcription factor 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330044( (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-...)
Affinity DataIC50:  1.00E+4nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330044( (2S,5R)-N—((S)-1-(2,4-difluorophenyl)-2,2,2-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent