BDBM3303 4-Anilinoquinazoline deriv. 54::4-N-(3-bromophenyl)quinazoline-4,6,7-triamine::4[ (3-Bromophenyl)aminol-6,7-diaminoquinazoline::CHEMBL328216

SMILES Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N

InChI Key InChIKey=ADXSZLCTQCWMTE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 3303   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50:  0.120nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50:  0.120nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of wild type EGFRChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of EGFR autophosphorylation in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3303(4-Anilinoquinazoline deriv. 54 | 4-N-(3-bromopheny...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed