BDBM330343 1-(3-{[(3R,6R)- 1-{[6-methoxy- 2-(2H-1,2,3- triazol-2-yl) pyridin-3-yl] carbonyl}-6- methyl- piperidin-3- yl]oxy} phenyl)ethanol::US9725434, 2::US9828368, Example 8
SMILES COc1ccc(C(=O)N2C[C@@H](CC[C@H]2C)Oc2cccc(c2)C(C)O)c(n1)-n1nccn1
InChI Key InChIKey=NZRHSDWEQBMOKT-XBOMOHCESA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 330343
Affinity DataIC50: 271nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:For intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the rat orexin-1 receptor or the human orexin-2 receptor, are gr...More data for this Ligand-Target Pair