BDBM330344 US9724435, Compound CM-356

SMILES CC(=O)c1ccc2oc(=O)n(CCCCN3CCN(CC3)c3ccc(F)cc3)c2c1

InChI Key InChIKey=NIKCPKNTCKAENL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330344   

TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University of Mississippi

US Patent
LigandPNGBDBM330344(US9724435, Compound CM-356)
Affinity DataKi:  1.21nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University of Mississippi

US Patent
LigandPNGBDBM330344(US9724435, Compound CM-356)
Affinity DataKi:  27.8nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent