BDBM330356 (1S)-1-cyclopropyl- 1-(2-{[(3R,6R)-6- methyl-1-{[2-(2H- 1,2,3-triazol-2-yl) phenyl]carbonyl} piperidin-3-yl]oxy} pyridin-4-yl)ethanol::US9725434, 12

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1cc(ccn1)[C@@](C)(O)C1CC1

InChI Key InChIKey=LDSZHRSIWREZPR-CVBYOTHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330356   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330356((1S)-1-cyclopropyl- 1-(2-{[(3R,6R)-6- methyl-1-{[2...)
Affinity DataIC50:  241nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330356((1S)-1-cyclopropyl- 1-(2-{[(3R,6R)-6- methyl-1-{[2...)
Affinity DataIC50:  13nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent