BDBM330371 (1S)-1-methyl-5-{[(3R,6R)-6-methyl-1-{[2-(2H-1,2,3-triazol-2-yl)phenyl]carbonyl}piperidin-3-yl]oxy}-1,2,3,4-tetrahydronaphthalen-1-ol::US9725434, 30

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccccc1-n1nccn1)Oc1cccc2c1CCC[C@]2(C)O

InChI Key InChIKey=PDPFULKDBIIJNM-UDCNLSRBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330371   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330371((1S)-1-methyl-5-{[(3R,6R)-6-methyl-1-{[2-(2H-1,2,3...)
Affinity DataIC50:  289nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM330371((1S)-1-methyl-5-{[(3R,6R)-6-methyl-1-{[2-(2H-1,2,3...)
Affinity DataIC50:  20nMAssay Description:The following table shows representative data for the compounds of the Examples as orexin receptor antagonists as determined by the FLIPR Ca2+ Flux A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent