BDBM331862 US10189853, Compound 7

SMILES CN(c1ccc2ccoc2c1)c1nc(C)nc2oc(C)cc12

InChI Key InChIKey=HFJIWOVMXXZSKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 331862   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM331862(US10189853, Compound 7)
Affinity DataIC50:  307nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM331862(US10189853, Compound 7)
Affinity DataIC50:  25nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Duquesne University of The Holy Spirit

US Patent
LigandPNGBDBM331862(US10189853, Compound 7)
Affinity DataIC50:  5.80nMAssay Description:RTK inhibitory activity of the compounds 2-12 were evaluated using human tumor cells known to express high levels of EGFR, VEGFR-2 or PDFGR-β us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent