BDBM33213 pyrazolopyridine, 12

SMILES NCC1CN(CCO1)c1c(Br)cnc2[nH]ncc12

InChI Key InChIKey=BJUBFXSKTBULRW-UHFFFAOYSA-N

Data  2 IC50  1 Other

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 33213   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute of Cancer Research

LigandPNGBDBM33213(pyrazolopyridine, 12)
Affinity DataIC50:  390nMpH: 7.5 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
The Institute of Cancer Research

LigandPNGBDBM33213(pyrazolopyridine, 12)
Affinity DatapH: 7.5 T: 2°CAssay Description:CDK1 kinase activity was measured in a DELFIA based HTScan CDK1/CycB kinase assay kit (Cell Signalling Technology) that monitors biotinylated substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute of Cancer Research

LigandPNGBDBM33213(pyrazolopyridine, 12)
Affinity DataIC50:  7.40E+3nMpH: 7.4 T: 2°CAssay Description:CHK kinase function was measured in a DELFIA assay in order to monitor phosphorylation of a CDC25C peptide using a specific phospho antibody. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed