BDBM332406 US10196353, Example 32::US11299457, Example 32

SMILES C[C@H](n1ccc2c(Cl)c(ccc12)C#N)C(C)(C)O

InChI Key InChIKey=GIBXFMCQBQGCKE-VIFPVBQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 332406   

TargetAndrogen receptor(Homo sapiens (Human))
Glaxosmithkline Intellectual Property (No. 2)

US Patent
LigandPNGBDBM332406(US10196353, Example 32 | US11299457, Example 32)
Affinity DataIC50:  31.6nMAssay Description:The androgen receptor fluorescence polarization assay is used to investigate the interaction of the compounds with the androgen receptor.Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgesterone receptor(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM332406(US10196353, Example 32 | US11299457, Example 32)
Affinity DataIC50:  31.6nMAssay Description:Compounds are added to the 384 well black low-volume plates to a final volume of 0.1 μL. DTT and DMSO are added to the chilled assay buffer just...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent