BDBM332763 Cis-(chiral)-N-[2-[5-(1,4- Dimethyl-1H-imidazol-5-yl)- 4H-1,2,4-triazol-3- yl]tetrahydro-2H-pyran-4- yl]-N-methyl-3- (trifluoromethoxy)benzamide, Isomer 1::US10196385, Example 2
SMILES CN([C@@H]1CCO[C@@H](C1)c1nnc([nH]1)-c1c(C)ncn1C)C(=O)c1cccc(OC(F)(F)F)c1
InChI Key
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332763
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Lilly China Research And Development Center (Lcrdc)
Curated by ChEMBL
Lilly China Research And Development Center (Lcrdc)
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human GPR142 receptor expressed in HEK293 cells assessed as accumulation of inositol phosphate incubated for 1 hr followed by IP1...More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 142(Homo sapiens (Human))
Lilly China Research And Development Center (Lcrdc)
Curated by ChEMBL
Lilly China Research And Development Center (Lcrdc)
Curated by ChEMBL
Affinity DataEC50: 30.1nMAssay Description:HEK293 cells expressing human GPR142 are maintained in DMEM supplemented with 10% FBS and 800 μg/ml G418 (Geneticin) at 37° C. and 5% CO2. The c...More data for this Ligand-Target Pair