BDBM332970 US10196390, Compound I-259::US10336752, Compound 11::US11040967, Compound 11

SMILES CCN(CC)C(=O)c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)cc1

InChI Key InChIKey=FEMLEBODPHKMLC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 332970   

TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332970(US10196390, Compound I-259 | US10336752, Compound ...)
Affinity DataKi: <10nMAssay Description:The caliper machine employs an off chip mobility shift assay to detect phosphorylated peptide substrates from kinase assays, using microfluidics tech...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332970(US10196390, Compound I-259 | US10336752, Compound ...)
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332970(US10196390, Compound I-259 | US10336752, Compound ...)
Affinity DataIC50:  119nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1x kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nimbus Lakshmi

US Patent
LigandPNGBDBM332970(US10196390, Compound I-259 | US10336752, Compound ...)
Affinity DataIC50:  119nMAssay Description:Compounds were serially diluted in DMSO then further diluted in 1× kinase buffer: 5 uL of buffer diluted compound was added into wells first, then 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent