BDBM33416 pyrimidinol carboxylic acid, 8

SMILES OC(=O)c1nc(CCc2ccccc2)[nH]c(=O)c1O

InChI Key InChIKey=OJDQPOULWGKJIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 33416   

TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences

LigandPNGBDBM33416(pyrimidinol carboxylic acid, 8)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences

LigandPNGBDBM33416(pyrimidinol carboxylic acid, 8)
Affinity DataIC50:  1.02E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed