BDBM335180 (4,5-Dimethyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2-(6-methoxy-1H-benzoimidazol-2-yl)-4-methylene-pyrrolidin-1-yl]-methanone::US11040966, Example 6.139::US9732075, Example 6.139

SMILES COc1ccc2nc([nH]c2c1)[C@@H]1CC(=C)CN1C(=O)c1cc(C)c(C)cc1-n1nccn1

InChI Key InChIKey=XSKYYULXLGRXSP-QFIPXVFZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 335180   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335180((4,5-Dimethyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2...)
Affinity DataIC50:  0.600nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM335180((4,5-Dimethyl-2-[1,2,3]triazol-2-yl-phenyl)-[(S)-2...)
Affinity DataIC50:  137nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent