BDBM335432 4-[(3R)-3-Aminopyrrolidin-1-yl]-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-2-amine::US9732087, 30

SMILES N[C@@H]1CCN(C1)c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=FFQSJNCCHVEUDV-SNVBAGLBSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 335432   

TargetHistamine H4 receptor(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM335432(4-[(3R)-3-Aminopyrrolidin-1-yl]-N-(tetrahydro-2H-p...)
Affinity DataKi:  42.4nMAssay Description:Cell pellets from SK-N-MC cells stably or transiently transfected with human H4 receptor (NCBI accession No. AF312230) were used for the binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent