BDBM337603 4-{[4'-(5-Aminopyrazin-2-yl)-3'- fluorobiphenyl-2-yl]oxy}benzoic acid::US9745328, Compound 888

SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1Oc1ccc(cc1)C(O)=O

InChI Key InChIKey=OULGGQYCBQOEMS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 337603   

TargetFlap endonuclease 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM337603(4-{[4'-(5-Aminopyrazin-2-yl)-3'- fluorobiphenyl-2-...)
Affinity DataKi:  0.700nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent