BDBM339159 US10201546, Example 80b::US10201546, Example 81b
SMILES COc1nc2ccc(cc2c(Cl)c1OC(C)C)[C@](O)(c1cnnn1C)c1cnc(C)n1C
InChI Key InChIKey=ISZZOCWVHYSXNA-JOCHJYFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 339159
Affinity DataKd: 19nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:For the RORγt construct used in the ThermoFluorŪ assay, numbering for the nucleotide sequences was based on the reference sequence for human ROR...More data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:A reporter assay was used to test functional activity of RORγt modulatory compounds on transcriptional activation driven by the RORγt LBD. ...More data for this Ligand-Target Pair