BDBM34010 benzothiophene carboxamide, 18b

SMILES OP(O)(=O)OC[C@@H](Cc1ccccc1)NC(=O)c1cc2ccccc2s1

InChI Key InChIKey=SXNKHSLGMRZBAC-OAHLLOKOSA-N

Data  1 KI  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 34010   

LigandPNGBDBM34010(benzothiophene carboxamide, 18b)
Affinity DataKi:  179nM ΔG°:  -8.89kcal/molepH: 7.5 T: 2°CAssay Description:The cis/trans conversion of cis-Suc-AEPFpNA peptide by the PPIase led to the cleavage of para nitroaniline by subtilisin which was monitored at 390 n...More data for this Ligand-Target Pair
LigandPNGBDBM34010(benzothiophene carboxamide, 18b)
Affinity DataKd:  72nMAssay Description:Binding affinity to full length Pin 1 (unknown origin) by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
LigandPNGBDBM34010(benzothiophene carboxamide, 18b)
Affinity DataIC50: <300nMAssay Description:Displacement of FITC-WFYpSPFLE from human Pin1 (45-163) catalytic domain by fluorescence polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM34010(benzothiophene carboxamide, 18b)
Affinity DataIC50:  180nMAssay Description:Inhibition of Pin1 (unknown origin)More data for this Ligand-Target Pair