BDBM341891 US9771320, Example 125

SMILES CCC(O)(c1ccc(cc1)C1(CCCC1)S(=O)(=O)c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=CJEPCVNMGKMCGZ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 341891   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM341891(US9771320, Example 125)
Affinity DataIC50:  98nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM341891(US9771320, Example 125)
Affinity DataEC50:  48nMAssay Description:Transactivation of PXR in human HepG2 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM341891(US9771320, Example 125)
Affinity DataEC50:  643nMAssay Description:Inverse agonist activity at GAL4-fused RORgammat LBD (267 to 516 residues) (unknown origin) expressed in human Jurkat cells measured after 18 hrs by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed