BDBM342 (3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({3-[(1E)-1-(hydroxyimino)ethyl]phenyl}methyl)-3,6-bis(phenoxymethyl)-1,2,7-thiadiazepane-1,1-dione::CHEMBL150626::Cyclic Sulfamide deriv. 20

SMILES CC(N=O)c1cccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3cccc(c3)C(C)N=O)S2(=O)=O)c1

InChI Key InChIKey=SXGGEMRFBQBUFK-OHHGTCQSSA-N

Data  2 KI  1 Kd  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 342   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM342((3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({3-[(1E)-1-(hy...)
Affinity DataKi:  3.40nM ΔG°:  -11.7kcal/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM342((3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({3-[(1E)-1-(hy...)
Affinity DataKi:  5.60nM Kd:  169nM Koff:  5.12E+5s-1Assay Description:Association rate constant for the interaction between inhibitor and HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM342((3R,4S,5S,6R)-4,5-dihydroxy-2,7-bis({3-[(1E)-1-(hy...)
Affinity DataKon:  0.0420M-1s-1Assay Description:Association rate constant for the interaction between inhibitor and HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed