BDBM34233 2-Phenyl-benzo[d]isoselenazol-3-one::2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen)::2-phenyl-1,2-benzisoselazol-3(2H)-one::2-phenyl-1,2-benzoselenazol-3-one::2-phenylbenzo[d][1,2]selenazol-3(2H)-one::CHEMBL51085::EBSELEN::Ebselen (C5)::MLS000028488::SMR000058445::cid_3194::med.21724, Compound 153

SMILES O=c1n([se]c2ccccc12)-c1ccccc1

InChI Key InChIKey=DYEFUKCXAQOFHX-UHFFFAOYSA-N

Data  10 KI  87 IC50  2 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 34233   

TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataKi:  1.20E+4nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataKi:  6.30E+4nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)
Affinity DataKi: >3.00E+5nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed