BDBM343270 4-(2,5-dimethylpyrimidin-4-yl)-N-(6-fluoro-2-(o-tolyl)-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-1-methyl-1H-pyrazole-5-carboxamide::US9777000, Example 3.5::US9777000, Example 3.50

SMILES Cc1ncc(C)c(n1)-c1cnn(C)c1C(=O)Nc1cc2nc(nn2cc1F)-c1ccccc1C

InChI Key InChIKey=ZLYRHFVATMYSAT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 343270   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM343270(4-(2,5-dimethylpyrimidin-4-yl)-N-(6-fluoro-2-(o-to...)
Affinity DataIC50: <5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Mochida Pharmaceutical

US Patent
LigandPNGBDBM343270(4-(2,5-dimethylpyrimidin-4-yl)-N-(6-fluoro-2-(o-to...)
Affinity DataIC50: <5nMAssay Description:IMAP TR-FRET Phosphodiersterase Evaluation Assay Kit (Molecular Device) was used for the measurement. Ten μL of a diluted test compound having e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent