BDBM344299 (+-)-(1S*,3S*)1-(3-fluoro-2-methylphenyl)-N-hydroxy-3-(o-tolyl)cyclopentane carboxamide::US9783488, Example 8

SMILES Cc1ccccc1[C@H]1CC[C@@](C1)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=RZUMZBGJTQFKEV-YWZLYKJASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344299   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM344299((+-)-(1S*,3S*)1-(3-fluoro-2-methylphenyl)-N-hydrox...)
Affinity DataIC50:  170nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent