BDBM344300 (1S,3S*)-1-(3-Fluoro-2- methyl-phenyl)-3-(5- fluoropyridin-3-yl)-N- hydroxycyclopentanecarboxamide::US9783488, Example 9

SMILES Cc1c(F)cccc1[C@@]1(CC[C@@H](C1)c1cncc(F)c1)C(=O)NO

InChI Key InChIKey=HZPQUCRMKHUJSP-SGTLLEGYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344300   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM344300((1S,3S*)-1-(3-Fluoro-2- methyl-phenyl)-3-(5- fluor...)
Affinity DataIC50:  150nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent