BDBM345069 4-[({5-[5-chloro-2-(1H- tetrazol-1-yl)phenyl]-1- oxidopyridin-2- yl}acetyl)amino] benzoic acid::US9783530, 14

SMILES OC(=O)c1ccc(NC(=O)Cc2ccc(c[nH+]2)-c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key InChIKey=SPQMIFYKMDUKTB-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 345069   

TargetKallikrein-1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM345069(4-[({5-[5-chloro-2-(1H- tetrazol-1-yl)phenyl]-1- o...)
Affinity DataIC50:  1.35E+3nMAssay Description:Kallikrein determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; Fishe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM345069(4-[({5-[5-chloro-2-(1H- tetrazol-1-yl)phenyl]-1- o...)
Affinity DataIC50:  18.6nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent