BDBM345228 (1S,3R)-3-(5-Fluoro-1-methyl-1H-indazol-6-yl)-1-(3-fluoro-2-methylphenyl)-N-hydroxycyclopentanecarboxamide::US9783488, Example 81

SMILES Cc1c(F)cccc1[C@@]1(CC[C@H](C1)c1cc2n(C)ncc2cc1F)C(=O)NO

InChI Key InChIKey=PXAMEPIPXDXIJJ-ASSNKEHSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345228   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM345228((1S,3R)-3-(5-Fluoro-1-methyl-1H-indazol-6-yl)-1-(3...)
Affinity DataIC50:  150nMAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent