BDBM347685 (E)-2-(4-Chlorophenoxy)-1-[2- (difluoromethoxy)phenyl]-3- (dimethylamino)prop-2-en-1-one::US9790217, 8

SMILES CN(C)\C=C(\Oc1ccc(Cl)cc1)C(=O)c1ccccc1OC(F)F

InChI Key InChIKey=UXDNMCWZZSZKNC-LFIBNONCSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347685   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347685((E)-2-(4-Chlorophenoxy)-1-[2- (difluoromethoxy)phe...)
Affinity DataEC50:  0.0760nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347685((E)-2-(4-Chlorophenoxy)-1-[2- (difluoromethoxy)phe...)
Affinity DataEC50:  0.00400nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent