BDBM347705 4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyloxy]-3-fluoro- benzonitrile ::US9790217, 28

SMILES CN(C)\C=C(\Oc1ccc(cc1F)C#N)C(=O)c1ccccc1Cl

InChI Key InChIKey=BUVOKCATNXSQII-GZTJUZNOSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347705   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347705(4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyl...)
Affinity DataEC50:  0.134nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347705(4-[(E)-1-(2-Chlorobenzoyl)-2- (dimethylamino)vinyl...)
Affinity DataEC50:  0.00200nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent