BDBM347707 4-[(E)-1-(3-Chloro-2-fluoro- benzoyl)-2- (dimethylamino)vinyloxy]benzonitrile::US9790217, 30

SMILES CN(C)\C=C(\Oc1ccc(cc1)C#N)C(=O)c1cccc(Cl)c1F

InChI Key InChIKey=ORKHYCOJCPDGES-LFIBNONCSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347707   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347707(4-[(E)-1-(3-Chloro-2-fluoro- benzoyl)-2- (dimethyl...)
Affinity DataEC50:  0.191nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347707(4-[(E)-1-(3-Chloro-2-fluoro- benzoyl)-2- (dimethyl...)
Affinity DataEC50:  0.00800nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent