BDBM347715 Methyl 3-[(Z)-2-(4-cyano-2-fluoro- phenoxy)-3-(dimethylamino)prop-2- enoyl]benzoate::US9790217, 38

SMILES COC(=O)c1cccc(c1)C(=O)C(\Oc1ccc(cc1F)C#N)=C\N(C)C

InChI Key InChIKey=LFXKALQIXFJREM-PDGQHHTCSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347715   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347715(Methyl 3-[(Z)-2-(4-cyano-2-fluoro- phenoxy)-3-(dim...)
Affinity DataEC50:  0.321nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347715(Methyl 3-[(Z)-2-(4-cyano-2-fluoro- phenoxy)-3-(dim...)
Affinity DataEC50:  0.0320nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent