BDBM347718 4-[(Z)-1-(2-Benzyloxybenzoyl)-2- (dimethylamino)vinyloxy]benzonitrile::US9790217, 41

SMILES CN(C)\C=C(/Oc1ccc(cc1)C#N)C(=O)c1ccccc1OCc1ccccc1

InChI Key InChIKey=WQMXZTIWJGZQQG-ULJHMMPZSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347718   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347718(4-[(Z)-1-(2-Benzyloxybenzoyl)-2- (dimethylamino)vi...)
Affinity DataEC50:  0.00100nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM347718(4-[(Z)-1-(2-Benzyloxybenzoyl)-2- (dimethylamino)vi...)
Affinity DataEC50:  0.000100nMAssay Description:G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent