BDBM349513 US10207991, Ex. Cpd. No. 28::US10611728, Example Compound 28::US11691947, Example 28
SMILES CC(C)Oc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O
InChI Key InChIKey=CZMKZNSLFDBBJT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 349513
Affinity DataKi: 11nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to Sigma 2-receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cognition Therapeutics
US Patent
Cognition Therapeutics
US Patent
Affinity DataKi: 120nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Cognition Therapeutics
US Patent
Cognition Therapeutics
US Patent
Affinity DataKi: 120nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cognition Therapeutics
US Patent
Cognition Therapeutics
US Patent
Affinity DataKi: 120nMAssay Description:Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...More data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cognition Therapeutics
US Patent
Cognition Therapeutics
US Patent
Affinity DataKi: 120nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cognition Therapeutics
Curated by ChEMBL
Cognition Therapeutics
Curated by ChEMBL
Affinity DataEC50: 9.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells measured by Patch-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Cognition Therapeutics
Curated by ChEMBL
Cognition Therapeutics
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Representative sigma-2 antagonists test compounds do not induce neuronal or glial toxicity with acute or chronic dosing in vitro. The sigma-2 recepto...More data for this Ligand-Target Pair