BDBM350015 6-(3-amino-6-(1- methyl-1H-pyrazol-4- yl)pyrazin-2-yl)-2-(2- chloro-3,5- dimethoxyphenyl)pyridazin- 3(2H)-one (2,2,2-trifluoroacetate) salt::US10208024, Example 14::US10766881, Example 14
SMILES COc1cc(OC)c(Cl)c(c1)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(C)c1
InChI Key InChIKey=CYWDLLRCEFUKME-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 350015
Affinity DataIC50: 6.30nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair