BDBM350075 6-(3-amino-6-(1- cyclopropyl-1H-pyrazol- 4-yl)pyrazin-2-yl)-2-(2,6- dichloro-3,5- dimethoxyphenyl)pyridazin- 3(2H)-one::US10208024, Example 74::US10766881, Example 74
SMILES COc1cc(OC)c(Cl)c(c1Cl)-n1nc(ccc1=O)-c1nc(cnc1N)-c1cnn(c1)C1CC1
InChI Key InChIKey=ADXIYSMNFMHFLE-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 350075
Affinity DataIC50: 5.80nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:To measure FGFR1 kinase activity, 200 pM His-tagged recombinant human FGFR1 catalytic domain (amino acids 308-731) (Life Technologies Cat. No. PR4660...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:FGFR1, 2 and 3 kinase activity was measured by the Invitrogen LanthaScreen™ Assay technology which directly measures the amount of substrate phosphor...More data for this Ligand-Target Pair