BDBM35053 K00486

SMILES CCC(CO)Nc1ccc2ncc(-c3ccc(F)c(Cl)c3)n2n1

InChI Key InChIKey=KWWMCDVDRSJVAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35053   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
University Hospital Basel

LigandPNGBDBM35053(K00486)
Affinity DataIC50:  2.50E+3nMpH: 7.5 T: 2°CAssay Description:Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
University Hospital Basel

LigandPNGBDBM35053(K00486)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed