BDBM352700 (S)-(2-(2-(methoxyamino)-2-oxoethyl)-4-((3-(trifluoromethyl)phenyl)sulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)carbamic Acid::US10745364, Example 44::US9809561, 44

SMILES CONC(=O)C[C@H]1CN(c2cc(NC(O)=O)ccc2O1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=JVNCOYKALIFDAS-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352700   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM352700((S)-(2-(2-(methoxyamino)-2-oxoethyl)-4-((3-(triflu...)
Affinity DataIC50:  4.07nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM352700((S)-(2-(2-(methoxyamino)-2-oxoethyl)-4-((3-(triflu...)
Affinity DataIC50:  4.07nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent