BDBM356575 N-[3-(7-{1-[2-(3-Hydroxyazetidin-1-yl)-1-methyl-2-oxoethyl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 64

SMILES CC(N\C=C(/C=N)c1cnn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1)C(=O)N1CC(O)C1

InChI Key InChIKey=KSOGSDANYBRCHC-AJUGCAFXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356575   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM356575(N-[3-(7-{1-[2-(3-Hydroxyazetidin-1-yl)-1-methyl-2-...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent